By Margareta Törnqvist (auth.), Mendel Friedman, Don Mottram (eds.)
Reports that warmth processing of meals induces the formation of acrylamide heightened curiosity within the chemistry, biochemistry, and protection of this compound. Acrylamide-induced neurotoxicity, reproductive toxicity, genotoxicity, and carcinogenicity are capability human overall healthiness hazards in keeping with animal experiences. simply because publicity of people to acrylamide can come from either exterior resources and the vitamin, there exists a necessity to advance a greater figuring out of its formation and distribution in nutrition and its function in human healthiness. To give a contribution to this attempt, specialists from 8 nations have offered information at the chemistry, research, metabolism, pharmacology, and toxicology of acrylamide.
Specifically lined are the next features: publicity from the surroundings and the nutrition; biomarkers of publicity; danger evaluation; epidemiology; mechanism of formation in nutrients; organic alkylation of amino acids, peptides, proteins, and DNA via acrylamide and its epoxide metabolite glycidamide; neurotoxicity, reproductive toxicity, and carcinogenicity; defense opposed to antagonistic results; and attainable methods to decreasing degrees in nutrients. Cross-fertilization of rules between a number of disciplines within which an curiosity in acrylamide has built, together with nutrition technology, pharmacology, toxicology, and drugs, will supply a greater figuring out of the chemistry and biology of acrylamide in nutrition, and will result in the advance of nutrition tactics to diminish the acrylamide content material of the diet.
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Chemistry and Safety of Acrylamide in Food by Margareta Törnqvist (auth.), Mendel Friedman, Don Mottram (eds.)