By Elena Burlakova, Sergey Dmitrievich Varfolomeev
The 1st quantity of this set is dedicated to the matter of chemical physics and actual chemistry of polymers and occasional molecular compounds. subject matters contain radical, ion and molecular reactions. Kinetics and mechanism of those reactions indicated a potential rules of price and the path of reactions.This quantity discusses questions of free-radical biology and new, smooth instructions in molecular cytobiology; proteomics and genomics. the second one quantity offers articles and reports on bioantioxidants, synthesis of latest compounds, mechanisms in their motion and components of software. reports on unfastened radical states utilizing ESR process, biochemistry of regulatory structures and the position of loose radicals in radiation affliction and melanoma improvement are given unique consciousness. try out result of new medicines for curing malignant tumors and kinetic methods to the outline of ailment improvement and estimation of healing motion of medicinal arrangements are proven. The booklet additionally offers reports within the department of enzymology, receptor platforms, photoreception, specifically. the quantity uniquely offers common trends in chemistry, biology and drugs kinetically united and hooked up to unfastened radical mechanisms and different questions into account
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Extra info for Chemical and biological kinetics; New horizons Vol 2
4 3. 5 4. 8 KM 6. 8 Km 7. 32 24 h after injection 8. 0 14 4 Table 6 shows results of such investigation. Amazingly, the range of changes and their directivity were practically equal for doses different by 1010 times. We would like to pay special attention to the change in gene expression, for example, p53 gene, which activity increased for 10~14 and 10~3 M doses. Despite different temporal dependence, the changes were of the same character. Thus the presence of close effects for usual and hyperlow doses cannot be explained from the viewpoint of antioxidant use of various biochemical mechanisms and targets in these concentration ranges.
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Spatially Hindered Phenols, Moscow, Khimia, 1972, 351 p. (Rus) 13. I. , Izv. AN SSSR, Ser. , 1963, No. 5, p. 890. (Rus) 14. , Bioantioxidants in Radiation Damage and Malignant Growth, Moscow, Nauka, 1975, 214 p. (Rus) 15. , Doklady AN SSSR, 1964, vol. 155, p. 1398. (Rus) 16. , Biofizika, 1971, vol. 16(2), p. 201. (Rus) Volume II. Biological Kinetics 29 17. , Izv. AN SSSR, Ser. , 1971, No. 2, p. 2714. (Rus) 18. , Biofizika, 1971, vol. 16(1), p. 39. (Rus) 19. , Biopolymers: Kinetics of Radiation and Photochemical Transformations, Moscow, Nauka, 1988,214 p.
Chemical and biological kinetics; New horizons Vol 2 by Elena Burlakova, Sergey Dmitrievich Varfolomeev