Cardiac Regeneration and Repair. Pathology and Therapies - download pdf or read online

By R-K Li and R.D. Weisel (Eds.)

ISBN-10: 0857096583

ISBN-13: 9780857096586

Cardiac Regeneration and service, quantity One stories the pathology of cardiac damage and the newest advances in mobilephone therapy.

Chapters partly one discover the pathogenesis of congestive center failure, the mechanisms accountable for hostile cardiac matrix home improvement, and capability interventions to revive ventricular functionality. half highlights new techniques to telephone remedy for cardiac regeneration, and comprises chapters overlaying alternative ways of mobile supply, tracking phone engraftment, and the feasibility of utilizing allogeneic stem cells to revive cardiac functionality. Chapters partially 3 circulation directly to spotlight novel stem cells for cardiac fix, together with human embryonic stem cells and human pluripotent stem cells, and element their present prestige and destiny strength for cardiac treatment. ultimately, half 4 explores gene treatment, and comprises ultrasound-targeted or direct gene supply in addition to cell-based gene treatment for cardiac regeneration.

Cardiac Regeneration and service, quantity One is complemented by way of a moment quantity protecting biomaterials and tissue engineering. jointly, the 2 volumes of Cardiac Regeneration and Repair supply a accomplished source for clinicians, scientists, or academicians interested by cardiac regeneration, together with these drawn to mobilephone treatment, tissue engineering, or biomaterials.

  • Explores the pathogenesis of congestive center failure, the mechanisms answerable for antagonistic cardiac matrix home improvement, and capability interventions to revive ventricular function
  • Highlights new methods to phone remedy for cardiac regeneration and contains chapters protecting alternative ways of phone supply, tracking telephone engraftment, and the feasibility of utilizing allogeneic stem cells to revive cardiac function
  • Explores gene remedy and contains ultrasound-targeted or direct gene supply in addition to cell-based gene treatment for cardiac regeneration

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Sample text

Spinale FG, Coker ML, Krombach SR, et al. (1999) Matrix metalloproteinase inhibition during the development of congestive heart failure: effects on left ventricular dimensions and function. Circ Res 85: 364–376. 72. Rohde LE, Ducharme A, Arroyo LH, et al. (1999) Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice. Circulation 99: 3063–3070. 73. Mukherjee R, Brinsa TA, Dowdy KB, et al. (2003) Myocardial infarct expansion and matrix metalloproteinase inhibition.

71. Spinale FG, Coker ML, Krombach SR, et al. (1999) Matrix metalloproteinase inhibition during the development of congestive heart failure: effects on left ventricular dimensions and function. Circ Res 85: 364–376. 72. Rohde LE, Ducharme A, Arroyo LH, et al. (1999) Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice. Circulation 99: 3063–3070. 73. Mukherjee R, Brinsa TA, Dowdy KB, et al. (2003) Myocardial infarct expansion and matrix metalloproteinase inhibition.

For imaging methods that can only measure strains on the surface of the heart, Kelly et al. (2007) proposed to quantify regional function using two-dimensional analogs of the global parameters: stroke volume and stroke work. To compute these parameters, regional work loops (Fig. 1b) can be calculated based on changes in area of heart regions. These regional work loops are produced by plotting pressure against normalized regional area change. From these regional work loops, regional stroke work (RSW, Eq.

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Cardiac Regeneration and Repair. Pathology and Therapies by R-K Li and R.D. Weisel (Eds.)


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