Download e-book for kindle: BioMEMS and Biomedical Nanotechnology: Biomolecular Sensing, by Rashid Bashir, Mauro Ferrari, Steven T. Wereley

By Rashid Bashir, Mauro Ferrari, Steven T. Wereley

ISBN-10: 0387255664

ISBN-13: 9780387255668

ISBN-10: 038725661X

ISBN-13: 9780387256610

Volume four of the multi-volume reference, BioMEMS and Biomedical Nanotechnology В is a balanced evaluation of key points of BioMEMS sensors, together with (i) BioMEMS sensors and fabrics, (ii) technique of manipulating organic entities on the microscale, and (iii) micro-fluidics and characterization. those 3 sections supply a succinct assessment of significant themes inside a unmarried volume.

This quantity is especially good illustrated with the various figuresВ in color.

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Additional info for BioMEMS and Biomedical Nanotechnology: Biomolecular Sensing, Processing and Analysis

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Printing proteins as microarrays for high-throughput function determination. Science, 289:1760, 2000. [18] R. Marie, H. Jensenius, J. B. Christensen, and A. Boisen. Adsorption kinetics and mechanical properties of thiol-modified DNA-oligos on gold investigated by microcantilever sensors. Ultramicroscopy, 91:29, 2002. [19] R. McKendry, J. Zhang, Y. Arntz, T. Strunz, M. P. K. Baller, U. Certa, E. J. Guntherodt, and C. Gerber. Multiple label-free biodetection and quantitative DNA-binding assays on a nanomechanical cantilever array.

Coli O157:H7. The application of a biochip using the molecular beacon (MB) detection scheme has been reported [Culha et al, 2004]. The medical application of this biochip novel MB detection system for the analysis of the breast cancer gene BRCA1 was illustrated. The MB is designed for the BRCA1 gene and a miniature biochip system is used for detection. The detection of BRCA1 gene is successfully demonstrated in solution and the limit of detection (LOD) is estimated as 70 nM. 4. CONCLUSION For practical medical diagnostic applications, there is currently a strong need for a truly integrated biochip system that comprises probes, samplers, detector as well as amplifier and logic circuitry.

38 × 10−23 J/K), T is the absolute temperature (300 K at room temperature), B is the bandwidth of measurement (typically about 1000 Hz for dc measurement), f 0 is the resonance frequency of the cantilever, k is the cantilever stiffness, and Q is the quality factor of the resonance with is related to damping (in liquid Q ∼ 1). Thermal vibration noise of silicon or silicon nitride cantilevers generally falls in the sub-nm range, which is negligible compared to noise from the detection system. The practical sensing limitation by noise will be discussed in the following for each detection technique.

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BioMEMS and Biomedical Nanotechnology: Biomolecular Sensing, Processing and Analysis by Rashid Bashir, Mauro Ferrari, Steven T. Wereley


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