By Icon Health Publications
This can be a 3-in-1 reference ebook. It provides a whole clinical dictionary masking 1000s of phrases and expressions in terms of basal ganglia. It additionally provides wide lists of bibliographic citations. eventually, it offers details to clients on easy methods to replace their wisdom utilizing a number of web assets. The publication is designed for physicians, scientific scholars getting ready for Board examinations, clinical researchers, and sufferers who are looking to get to grips with learn devoted to basal ganglia. in the event that your time is effective, this publication is for you. First, you won't waste time looking out the web whereas lacking loads of appropriate details. moment, the booklet additionally saves you time indexing and defining entries. eventually, you won't waste money and time printing hundreds of thousands of web content.
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Additional resources for Basal Ganglia - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
To identify the potential intermediary role of secondary genes functionally downstream of HPRT activity, we have used microarray gene expression analysis on commercially available MU74 oligonucleotide mouse genome chips that interrogate approximately 12,000 known genes and ESTs. In preliminary comparisons of gene expression in dissected striata from wild type and HPRT-deficient mice, we have detected reproducible changes in the expression of a small number of genes and ESTs, including those encoding translation initiation factors IF2s3 and IF3s1, genes associated with striatal dopaminergic neuron function such as sepiapterin reductase that regulates expression of the tetrahydrobiopterin co-factor of tyrosine hydroxylase, and casein kinase I-epsilon that phosphorylates DARPP-32, the principal striatal target for dopamine function.
Finally, asymmetries in gestural communication and facial expressions will be correlated with asymmetries in the brain from specific regions of interest including the planum temporale, Brodmann's area 44, the motor/hand area of the precentral gyrus, cingulate gyrus and basal ganglia. Of specific interest in all analyses will be, the comparison of chimpanzee subjects that have been reared by human compared to those reared by chimpanzees. This comparison will allow for determination of how human environments and communication systems alter the development of communicative behavior and the cerebral organization of chimpanzees.
To accomplish these goals, we will assess the effects of intrastriatal injections of virotoxins in animals treated with methamphetamine and in vitro in human cortical neurons where cell types can be manipulated. ; Pharmacology and Toxicology; University of Utah Salt Lake City, Ut 84102 Timing: Fiscal Year 2002; Project Start 01-OCT-2002; Project End 31-JUL-2003 Summary: (provided by applicant) Substituted amphetamines, such as methamphetamine (METH), produce long-lasting, partial loss of central monoamine systems.
Basal Ganglia - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications