By Icon Health Publications
This can be a 3-in-1 reference booklet. It provides a whole scientific dictionary overlaying thousands of phrases and expressions in relation to apnea. It additionally offers wide lists of bibliographic citations. eventually, it presents details to clients on how you can replace their wisdom utilizing a variety of net assets. The ebook is designed for physicians, clinical scholars getting ready for Board examinations, clinical researchers, and sufferers who are looking to get to grips with learn devoted to apnea. in case your time is effective, this ebook is for you. First, you won't waste time looking the net whereas lacking loads of proper info. moment, the e-book additionally saves you time indexing and defining entries. ultimately, you won't waste time and cash printing hundreds of thousands of websites.
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Extra info for Apnea - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
Specific Aim 1 will examine the impact of repetitive intermittent hypoxia during sleep on carotid body function in a novel, murine model of sleep disordered breathing. Specific Aim 2 will investigate the pattern of acetylcholine and other neurotransmitter release from the carotid body, as well as recording carotid sinus nerve activity, in response to repetitive intermittent hypoxia. Specific Aim 3 will use immunohistochemical and patch clamp analyses to determine if neuronal nicotinic acetylcholine receptors (nAChRs) can account for differential hypoxic responsiveness between mouse strains with differential hypoxic responsiveness and determine whether repetitive intermittent hypoxia upregulates expression of subtypes of nAChRs.
A second dog model as well as human patients with chronic heart failure will be studied to address the mechanisms of Cheyne-Stokes respiration, with specific emphasis on the effects of the added stimulus to hyperventilation originating from the lungs of the patient in congestive heart failure. Finally, we will use dogs and humans-with and without innervated lungs-to address the role of non-chemical, mechanoreceptor inhibitory feedback effects during sleep on upper airway and pump muscles; a) influences from high frequency low amplitude pressure oscillations in the upper airway; b) the effects of amplitude, timing and duration of normocapnic mechanical ventilation on the resetting of inherent respiratory rhythm and on the "shortterm inhibition" of respiratory motor output following cessation of phasic inhibitory sensory input.
Because up to 30% of patients with epilepsy continue to have seizures despite appropriate treatment with antiepileptic medications, additional interventions to improve seizure control are needed. One approach to improving seizure control is to treat coexisting sleep disorders, such as obstructive sleep apnea. Obstructive sleep apnea (OSA) may exacerbate seizures via sleep fragmentation, sleep deprivation, or other pathophysiological processes that have not yet been determined. The investigators recently documented that OSA is common in epilepsy patients with seizures refractory to medical treatment.
Apnea - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References by Icon Health Publications