By Jay D. Humphrey, Sherry L. O'Rourke
Designed to fulfill the desires of undergraduate scholars, Introduction to Biomechanics takes the clean strategy of mixing the viewpoints of either a well-respected instructor and a profitable scholar. With a watch towards practicality with out lack of intensity of guideline, this ebook seeks to provide an explanation for the basic suggestions of biomechanics. With the accompanying website supplying types, pattern difficulties, assessment questions and extra, Introduction to Biomechanics offers scholars with the whole variety of educational fabric for this complicated and dynamic box.
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Additional info for An Introduction to Biomechanics: Solids and Fluids, Analysis and Design
Free-body diagrams of the whole structure and the individual parts reveal that the reaction and internal forces are the same: Ry =h = W; that is, from the perspective of statics alone, these two problems are equivalent. Nevertheless, intuition tells us that the behavior of member A need not be the same as that of member B. One may fail before the other. An important question to be answered by mechanics, therefore, may be the following: Which member will likely fail first given increasing weights W?
Elastin is synthesized in minutes, as the precursor proelastin, via normal pathways-mRNA, endoplasmic reticulum, Golgi apparatus, and so forth. Moreover, it appears that synthesis can be assumed to be a first-order process, one that is completed in less than 1 h (Davidson and Giro, 1986). In the vasculature, this synthesis is accomplished primarily by smooth muscle, but also by specialized fibroblasts and, perhaps, endothelial cells. Once secreted into the extracellular space, the soluble proelastin is cross-linked to form the insoluble (stable) elastin meshwork.
Cross-links can be either reducible or nonreducible; reducible cross-links can be broken, for example, during thermal treatment. 4 Overall, the degree of cross-linking tends to increase with age, which results in concomitant stiffening; pathological stiffening, via the addition of glycosylated cross-links, occurs in diabetes. Note, too, that collagen fibers are usually undulated at physiologic loads; thus, they exhibit their true stiffness only when straightened under the action of applied loads.
An Introduction to Biomechanics: Solids and Fluids, Analysis and Design by Jay D. Humphrey, Sherry L. O'Rourke